Targeting DNA in therapies: using damages to design strategies on cell sensitisation
نویسندگان
چکیده
منابع مشابه
Studies of DNA repair strategies in response to complex DNA damages
The main aim of this thesis was to study the role of the indirect actions of γ-rays and αparticles on the complexity of primary DNA damages and the repair fidelity of major DNA repair pathways: non-homologous end joining (NHEJ), homologous recombination repair (HRR) and base excision repair (BER). The complexity of radiation-induced damages increases and the proximity between damages decreases ...
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ژورنال
عنوان ژورنال: Journal of Physics: Conference Series
سال: 2008
ISSN: 1742-6596
DOI: 10.1088/1742-6596/101/1/012013